Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study

Raffaele Brustia (1) , Serena Langella , Takayuki Kawai , Gilton Marques Fonseca , Astrid Schielke (1) , Fabio Colli , Vivian Resende , Francesco Fleres (2) , Didier Roulin , Paul Leyman , Alessandro Giacomoni , Benjamin Granger (3) , Laetitia Fartoux (4) , Luciano de Carlis , Nicolas Demartines (5) , Daniele Sommacale (2) , Marcelo Dias Sanches , Damiano Patrono (6) , Olivier Detry (7) , Paulo Herman , Shinya Okumura , Alessandro Ferrero , Olivier Scatton (8) , Shinji Uemoto , Fabiano Perdigao (1) , Francisco Nolasco , Sophie Laroche , Renato Romagnoli , Simone Famularo

1 CHU Pitié-Salpêtrière [AP-HP]
2 Hôpital universitaire Robert Debré [Reims]
3 GRC-08 EEMOIS - Épidémiologie et Évaluation des Maladies Ostéoarticulaires Inflammatoires et Systémiques
4 Service d'Hépato-Gastro-Enterologie et Nutrition [CHU Caen]
5 CHUV - Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital [Lausanne]
6 Service de Chirurgie Digestive / Centre de Transplantation Hépatique [CHU Nice]
7 CHU-Liège - Centre Hospitalier Universitaire de Liège
8 CRSA - Centre de Recherche Saint-Antoine

A preoperative risk score (PRS) to predict outcome of patients with intrahepatic cholangiocarcinoma treated by liver surgery could be clinically relevant.To assess accuracy for broadly adoption, external validation of predictive models on independent datasets is crucial. The objective of this study was to externally validate the score for prediction of long-term outcomes after liver surgery for intrahepatic cholangiocarcinoma proposed by Sasaki et al. and based on preoperative albumin, neutrophil-to-lymphocytes-ratio, CA19-9 and tumor size.

Mots clés: External validation; Intra-hepatic cholangiocarcinoma; Liver surgery; Long-term outcomes; Prognostic score

Domaines: Chirurgie; Hépatologie et Gastroentérologie

Raffaele Brustia, Serena Langella, Takayuki Kawai, Gilton Marques Fonseca, Astrid Schielke, et al.. Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study. EJSO - European Journal of Surgical Oncology, 2019, ⟨10.1016/j.ejso.2019.10.041⟩. ⟨hal-02366507⟩