Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study

Raffaele Brustia; Serena Langella; Takayuki Kawai; Gilton Marques Fonseca; Astrid Schielke; Fabio Colli; Vivian Resende; Francesco Fleres; Didier Roulin; Paul Leyman; Alessandro Giacomoni; Benjamin Granger; Laetitia Fartoux; Luciano de Carlis; Nicolas Demartines; Daniele Sommacale; Marcelo Dias Sanches; Damiano Patrono; Olivier Detry; Paulo Herman; Shinya Okumura; Alessandro Ferrero; Olivier Scatton; Shinji Uemoto; Fabiano Perdigao; Francisco Nolasco; Sophie Laroche; Renato Romagnoli; Simone Famularo

doi:10.1016/j.ejso.2019.10.041

Journal articles

Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study

Raffaele Brustia ¹ Serena Langella Takayuki Kawai Gilton Marques Fonseca Astrid Schielke ² Fabio Colli Vivian Resende Francesco Fleres ³ Didier Roulin Paul Leyman Alessandro Giacomoni Benjamin Granger ⁴ Laetitia Fartoux ⁵ Luciano de Carlis Nicolas Demartines ⁶ Daniele Sommacale ³ Marcelo Dias Sanches Damiano Patrono ⁷ Olivier Detry ⁸ Paulo Herman Shinya Okumura Alessandro Ferrero Olivier Scatton ⁹ Shinji Uemoto Fabiano Perdigao ¹⁰ Francisco Nolasco Sophie Laroche Renato Romagnoli Simone Famularo

1 CHU Pitié-Salpêtrière [AP-HP]

2 Service de chirurgie digestive hépato-bilio-pancréatique transplantation hépatique [CHU Pitié-Salpêtrière]

3 Service de Chirurgie Générale, Digestive et Endocrine [CHU Reims]

4 GRC-08 EEMOIS - Service de rhumatologie [CHU Pitié Salpêtrière]

5 Service d'Hépato-Gastro-Enterologie et Nutrition [CHU Caen]

6 CHUV - Centre Hospitalier Universitaire Vaudois [Lausanne]

7 Service de Chirurgie Digestive et Transplantation Hépatique

8 CHU-Liège - Centre Hospitalier Universitaire de Liège

9 CR Saint-Antoine - Centre de Recherche Saint-Antoine

10 Unité de Transplantation Hépatique

Abstract : A preoperative risk score (PRS) to predict outcome of patients with intrahepatic cholangiocarcinoma treated by liver surgery could be clinically relevant.To assess accuracy for broadly adoption, external validation of predictive models on independent datasets is crucial. The objective of this study was to externally validate the score for prediction of long-term outcomes after liver surgery for intrahepatic cholangiocarcinoma proposed by Sasaki et al. and based on preoperative albumin, neutrophil-to-lymphocytes-ratio, CA19-9 and tumor size.

Keywords : Liver surgery Intra-hepatic cholangiocarcinoma External validation Prognostic score Long-term outcomes

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Journal articles

Domain :

Life Sciences [q-bio] / Human health and pathology / Surgery

Life Sciences [q-bio] / Human health and pathology / Hépatology and Gastroenterology

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Submitted on : Friday, November 15, 2019 - 11:09:04 PM
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Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study

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Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study

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