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Habilitation à diriger des recherches

Combinatorial Objects in Bio-Algorithmics: Related problems and complexities

Abstract : The aim of this habilitation is to exhibit my contributions in several area of Bio-Algorithmics. Rather than an exhaustive presentation of my works, I have made the choice of presenting results we obtained with collaborators on a representative subset of the problems I have been involved in since 2005. For ease of readability, I will regroup the results obtained according to the biological problems: i) RNA structures comparison, ii) Genomes comparison and iii) Pattern matching in biological networks and their respective combinatorial objects: i) Arc-annotated sequences, ii) Permutations and Sequences and iii) Graphs. More precisely, The first part will be devoted to the Arc-Annotated Sequences that are used in RNA structure comparison. We will focus on five problems that we investigated: LAPCS, APS, MAPCS, EDIT and ALIGN. In the second part, we will consider the two main research area related to comparative genomics we were involved in: gene clusters detection and (dis)similarity measures computation -- which rely on permutation and string representations. Finally, we will present some results that were obtained mainly during the PhD of Florian Sikora that I co-supervised.
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Habilitation à diriger des recherches
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https://tel.archives-ouvertes.fr/tel-00711879
Contributor : Guillaume Blin <>
Submitted on : Tuesday, June 26, 2012 - 8:17:55 AM
Last modification on : Wednesday, February 3, 2021 - 7:54:26 AM
Long-term archiving on: : Thursday, December 15, 2016 - 6:29:51 PM

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  • HAL Id : tel-00711879, version 1

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Guillaume Blin. Combinatorial Objects in Bio-Algorithmics: Related problems and complexities. Bioinformatics [q-bio.QM]. Université Paris-Est, 2012. ⟨tel-00711879⟩

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