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3D shaped mechanically flexible diamond microelectrode arrays for eye implant applications: The MEDINAS project Matrices d’électrodes en diamant pour l’interfaçage neuronal appliqué à la suppléance fonctionnelle (MEDINAS)

P. Bergonzo 1 Alexandre Bongrain 2, 1 Emmanuel Scorsone 1 A. Bendali 3 L. Rousseau 2 Gaelle Bazin Lissorgues 2 P. Mailley 4 y. Li 5 T. Kauffmann 6 F. Goy 6 B. yvert 5 José-Alain Sahel 3, 7 S. Picaud 3, 7 
1 LCD-LIST - Laboratoire Capteurs Diamant
DM2I - Département Métrologie Instrumentation & Information : DRT/LIST/DM2I
2 ESIEE Paris
3 INSERM - Institut National de la Santé et de la Recherche Médicale
4 SPRAM - UMR 5819 - Structures et propriétés d'architectures moléculaire
5 INCIA - Institut de Neurosciences cognitives et intégratives d'Aquitaine
6 Bio-Logic SAS
7 Fondation Ophtalmologique Adolphe de Rothschild [Paris]
Abstract : The MEDINAS project aims at the fabrication of Micro-Electrode Arrays (MEA) that take advantage of a novel electrode material, namely synthetic conducting diamond, as the bio-interface material. Diamond enables the fabrication of electrodes with high biocompatibility, high electrochemical interfacing performances and long-term stability. The project aims at the development of diamond based MEAs for recording and stimulating of neuron networks for both in vitro applications (rigid substrate) as well as for in vivo retinal prostheses (flexible biocompatible substrate). The performances of this new technology were assessed as compared to standard metallic solutions.
Keywords : Neurobiological interfaces instrumentation Chemical Vapor Deposition (CVD) diamond thin film Retina implant biocompatibility long-term stability neuron stimulation retinal prostheses Micro-Electrode Arrays
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https://hal-upec-upem.archives-ouvertes.fr/hal-00692916
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Submitted on : Tuesday, June 28, 2022 - 6:58:19 PM
Last modification on : Thursday, July 7, 2022 - 6:12:35 AM

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CEA | UPEC-UPEM | CNRS | UNIV-MLV | ESYCOM | CV_ESYCOM | INAC-SPRAM | DRT | INC-CNRS | LRN | CEA-DRF | LIST | ESIEE-PARIS | IRIG | CEA-GRE | DM2I | ANR

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P. Bergonzo, Alexandre Bongrain, Emmanuel Scorsone, A. Bendali, L. Rousseau, et al.. 3D shaped mechanically flexible diamond microelectrode arrays for eye implant applications: The MEDINAS project Matrices d’électrodes en diamant pour l’interfaçage neuronal appliqué à la suppléance fonctionnelle (MEDINAS). Innovation and Research in BioMedical engineering, Elsevier Masson, 2011, 32 (2), pp.91--94. ⟨10.1016/j.irbm.2011.01.032⟩. ⟨hal-00692916⟩

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